Transposition protein of Tn3: identification and characterisation of an essential repressor-controlled gene product

Nature. 1979 Dec;282(5741):801-6. doi: 10.1038/282801a0.

Abstract

Fusions that bring lac gene expression under the control of transcriptional and translational signals within the Tn3 element have been used to identify and characterise a Tn3-encoded 'transposase' (Tnp) peptide of MW 100,000 essential for transposition. The gene specifying this product is regulated by the Tn3 repressor protein and is part of a bidirectional genetic unit that includes the repressor gene.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Bacterial Proteins / genetics*
  • Base Sequence
  • DNA Transposable Elements*
  • Escherichia coli / genetics*
  • Genes
  • Genes, Regulator
  • Lac Operon
  • Molecular Weight
  • Plasmids*
  • Protein Biosynthesis
  • Repressor Proteins / genetics*
  • Transcription Factors / genetics*
  • Transcription, Genetic

Substances

  • Bacterial Proteins
  • DNA Transposable Elements
  • Repressor Proteins
  • Transcription Factors

Associated data

  • GENBANK/J01832