Studies in vivo on the relationship between brain tryptophan, brain 5-HT synthesis and hyperactivity in rats treated with a monoamine oxidase inhibitor and L-tryptophan

J Neurochem. 1971 Jun;18(6):1053-66. doi: 10.1111/j.1471-4159.1971.tb12034.x.
No abstract available

MeSH terms

  • 5-Hydroxytryptophan / metabolism
  • Amines
  • Amino Acids / analysis
  • Animals
  • Brain Chemistry*
  • Carboxy-Lyases / metabolism
  • Dopamine / analysis
  • Fenclonine / pharmacology
  • Fever
  • Humans
  • Hyperkinesis*
  • Male
  • Mixed Function Oxygenases / metabolism
  • Monoamine Oxidase / metabolism
  • Monoamine Oxidase Inhibitors / pharmacology*
  • Motor Activity / drug effects
  • Neurons / metabolism
  • Norepinephrine / analysis
  • Rats
  • Reserpine / pharmacology
  • Serotonin / analysis
  • Serotonin / biosynthesis*
  • Serotonin / metabolism
  • Tetrabenazine / pharmacology
  • Time Factors
  • Tranylcypromine / pharmacology
  • Tryptophan / administration & dosage
  • Tryptophan / analysis
  • Tryptophan / blood
  • Tryptophan / metabolism*
  • Tryptophan / pharmacology*

Substances

  • Amines
  • Amino Acids
  • Monoamine Oxidase Inhibitors
  • Serotonin
  • Tranylcypromine
  • Reserpine
  • Tryptophan
  • 5-Hydroxytryptophan
  • Mixed Function Oxygenases
  • Monoamine Oxidase
  • Carboxy-Lyases
  • Fenclonine
  • Dopamine
  • Norepinephrine
  • Tetrabenazine