Cell surface coatings and membrane potentials of malignant and nonmalignant cells

Science. 1970 Aug 7;169(3945):601-3. doi: 10.1126/science.169.3945.601.

Abstract

A positive surface potential indicating a cell coating is common to malignant cells, lymphocytes, and normal and malignant trophoblastic cells. This characteristic was not generally found for other normal cell types tested by microelectrode penetration.

MeSH terms

  • Animals
  • Carcinoma / physiopathology
  • Cell Line / physiopathology
  • Cell Membrane*
  • Electrodes
  • Female
  • Haplorhini
  • HeLa Cells / physiopathology
  • Humans
  • Hydrogen-Ion Concentration
  • In Vitro Techniques
  • Kidney
  • Laryngeal Neoplasms / physiopathology
  • Lung
  • Membrane Potentials*
  • Mucins / analysis*
  • Neuraminic Acids
  • Pregnancy
  • Rats
  • Sarcoma, Experimental / physiopathology
  • Surface Properties*
  • Trophoblastic Neoplasms / physiopathology*

Substances

  • Mucins
  • Neuraminic Acids