Acetaminophen-induced hepatic necrosis. II. Role of covalent binding in vivo

MeSH terms

• Acetaminophen*
• Animals
• Carbon Radioisotopes
• Cell Nucleus / metabolism
• Chemical and Drug Induced Liver Injury / etiology*
• Cobalt / pharmacology
• In Vitro Techniques
• Liver / cytology
• Liver / metabolism
• Liver Diseases / metabolism
• Male
• Mice
• Mice, Inbred Strains
• Microsomes, Liver / metabolism
• Mitochondria, Liver / metabolism
• Necrosis / chemically induced
• Necrosis / metabolism
• Phenobarbital / pharmacology
• Piperonyl Butoxide / pharmacology
• Protein Binding / drug effects
• Time Factors
• Tritium