Catalase and dehydroascorbate reductase in human polymorphonuclear leukocytes (PMN): possible functional relationship

Experientia. 1979 Jul 15;35(7):852-3. doi: 10.1007/BF01955106.

Abstract

In leukocytes (PMN) of individuals with Swiss type acatalasemia, the rate of dehydroascorbate reduction is 4 times normal. This observation suggests that the protective function served by catalase in human PMN is supported by dehydroascorbate reductase.

MeSH terms

  • Acatalasia
  • Catalase / blood*
  • Dehydroascorbic Acid
  • Glutathione Peroxidase / blood
  • Glutathione Reductase / blood
  • Heterozygote
  • Homozygote
  • Humans
  • NADH, NADPH Oxidoreductases / blood*
  • Neutrophils / enzymology*
  • Phagocytosis
  • Superoxide Dismutase / blood

Substances

  • Catalase
  • Glutathione Peroxidase
  • Superoxide Dismutase
  • NADH, NADPH Oxidoreductases
  • Glutathione Reductase
  • Dehydroascorbic Acid