The location of the genes coding for hexon and fiber proteins in adenovirus DNA

Cell. 1975 May;5(1):93-9. doi: 10.1016/0092-8674(75)90097-5.

Abstract

A serological analysis has been made of the capsid antigens hexon and fiber from 17 Ad5-Ad2+ND1 recombinants that enables us to determine the phenotype of the recombinants. By correlation of this data with the genetic and physical maps of the adenovirus genome, obtained by recombination and restriction endonuclease analysis, the genes coding for the hexon and fiber have been assigned to specific locations on the adenovirus DNA.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adenoviridae / analysis*
  • Antigens, Viral*
  • Chromosome Mapping
  • Complement Fixation Tests
  • DNA, Viral / analysis*
  • Endonucleases / metabolism
  • Epitopes
  • Genes*
  • Genetic Code
  • Immunodiffusion
  • Mutation
  • Phenotype
  • Recombination, Genetic
  • Serotyping
  • Viral Proteins / biosynthesis*
  • Viral Proteins / immunology

Substances

  • Antigens, Viral
  • DNA, Viral
  • Epitopes
  • Viral Proteins
  • Endonucleases