Phytohemagglutinin: inhibition of the agglutinating activity by N-acetyl-D-galactosamine

H Berberg; J Woodruff; R Hirschhorn; B Gesner; P Miescher; R Silber

doi:10.1126/science.154.3752.1019

Phytohemagglutinin: inhibition of the agglutinating activity by N-acetyl-D-galactosamine

Science. 1966 Nov 25;154(3752):1019-20. doi: 10.1126/science.154.3752.1019.

Authors

H Berberg, J Woodruff, R Hirschhorn, B Gesner, P Miescher, R Silber

PMID: 5921884
DOI: 10.1126/science.154.3752.1019

Abstract

The effect of simple sugars on the agglutinating activity of phytohemagglutinin was studied. N-Acetyl-d-galactosamine selectively inhibits the agglutination of leukocytes and erythro- cytes by phytohemagglutinin.

MeSH terms

Amino Sugars / pharmacology*
Animals
Erythrocytes / drug effects*
Fucose / pharmacology*
Galactose / pharmacology*
Glucose / pharmacology*
Humans
Lectins / pharmacology*
Lymphocytes / drug effects*
Mannose / pharmacology*
Palatine Tonsil
Rabbits
Rats
Thoracic Duct
Thymus Gland

Substances

Amino Sugars
Lectins
Fucose
Glucose
Mannose
Galactose