Restriction fragment length polymorphisms at the human parathyroid hormone gene locus

Hum Genet. 1984;67(4):428-31. doi: 10.1007/BF00291404.

Abstract

Two common Pst I and Taq I restriction enzyme fragment length polymorphisms (RFLPs) were detected at the human parathyroid hormone (PTH) gene locus. The allele frequencies in a Northern German population were 0.578/0.422 (Pst I) and 0.628/0.372 (Taq I). The allele distributions follow Hardy-Weinberg expectations of equilibrium in the population. The Mendelian nature of the polymorphisms were confirmed in family studies.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alleles
  • Chromosome Mapping
  • DNA / genetics*
  • DNA Restriction Enzymes
  • Female
  • Gene Frequency
  • Genes*
  • Genetic Markers*
  • Humans
  • Male
  • Parathyroid Hormone / genetics*
  • Pedigree
  • Polymorphism, Genetic*

Substances

  • Genetic Markers
  • Parathyroid Hormone
  • DNA
  • DNA Restriction Enzymes