The nasal smear for eosinophils. Its value in children with seasonal allergic rhinitis

Am J Dis Child. 1982 Nov;136(11):1009-11. doi: 10.1001/archpedi.1982.03970470053015.

Abstract

Nasal smears for eosinophils obtained by nose blowing and/or posterior nasopharyngeal swabbing were stained with Wright's or Hansel's stains and read in three groups of children aged 4 to 15 years: 65 with seasonal allergic rhinitis, 42 with perennial rhinitis and negative skin tests, and 70 nonallergic controls. Of smears obtained by either or both methods, 69%, 11%, and 7% were positive (greater than or equal to 4%) in the three groups, respectively. Almost identical results were obtained using only the nose-blowing method. In children with seasonal nasal symptoms, the nasal smear for eosinophils appears to be a reliable diagnostic test with moderately high sensitivity and high specificity.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Eosinophilia / etiology*
  • Exudates and Transudates / analysis*
  • Female
  • Humans
  • Male
  • Nasal Mucosa / metabolism*
  • Rhinitis, Allergic, Seasonal / complications
  • Rhinitis, Allergic, Seasonal / diagnosis*
  • Rhinitis, Allergic, Seasonal / metabolism
  • Staining and Labeling