Abstract
We studied lactate and pyruvate concentrations in CSF and blood of a patient with Kearns-Sayre syndrome (KSS), 3 patients with ocular myopathy and 11 normal control subjects. We found significant elevation of lactate and pyruvate in the CSF of the patient with KSS, suggesting a disorder of CNS lactate-pyruvate metabolism.
Publication types
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Case Reports
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Comparative Study
MeSH terms
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Adult
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Female
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Humans
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Kearns-Sayre Syndrome / cerebrospinal fluid*
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Kearns-Sayre Syndrome / pathology
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Lactates / cerebrospinal fluid*
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Male
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Middle Aged
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Mitochondria, Muscle / ultrastructure
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Ophthalmoplegia / cerebrospinal fluid*
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Pyruvates / cerebrospinal fluid*