Radiotherapy versus surgery in the treatment of cervix stage Ib cancer

Int J Radiat Oncol Biol Phys. 1983 Dec;9(12):1781-4. doi: 10.1016/0360-3016(83)90344-9.

Abstract

In the years 1971-77 we have treated 250 Stage Ib patients with cancers of the cervix. One hundred twenty-three (49.2%) underwent a radical surgery, 37 had a classical Wertheim-Meigs operation, and 86 had a lymphadenectomy that was extended to the lumbar-aortic region. When feasible, all patients received postoperative radium therapy on the vaginal vault. The remaining 127 patients received a complete course of radiotherapy. This was not a randomized clinical trial. In fact surgery was preferred for patients who were younger (mean age: 49.6 years) and more physically fit, while radiotherapy was the treatment chosen for those who were older (mean age: 57.7) and generally less fit or obese. The 5 year NED survival was 89.3% in the surgical group and 90.9% in the radiotherapy group (P less than .05). Four fatal complications were observed in the surgical group (3.2%). Rate and causes of failures or complications are analyzed in detail.

Publication types

  • Comparative Study

MeSH terms

  • Adenocarcinoma / pathology
  • Adenocarcinoma / radiotherapy*
  • Adenocarcinoma / surgery
  • Brachytherapy
  • Carcinoma / pathology
  • Carcinoma / radiotherapy*
  • Carcinoma / surgery
  • Cobalt Radioisotopes / administration & dosage
  • Combined Modality Therapy
  • Female
  • Humans
  • Lymph Node Excision
  • Lymphatic Metastasis
  • Neoplasm Staging
  • Postoperative Care
  • Radium / administration & dosage
  • Uterine Cervical Neoplasms / pathology
  • Uterine Cervical Neoplasms / radiotherapy*
  • Uterine Cervical Neoplasms / surgery

Substances

  • Cobalt Radioisotopes
  • Radium