The maternal pheromone of the rat: testing some assumptions underlying a hypothesis

Physiol Behav. 1983 Apr;30(4):539-43. doi: 10.1016/0031-9384(83)90217-2.

Abstract

Herein we report four experiments relating to the maternal pheromone of the rat that show (a) preweanling young consume pheromone-containing feces most conspicuously between 14 and 27 days; (b) they consume those feces preferentially; (c) such feces contain high levels of deoxycholic acid; and (d) preweanling young are deficient in deoxycholic acid. The data of these experiments lend support to the hypothesis that in responding to the pheromone the young ingest deoxycholic acid, a steroid believed to promote gut immunocompetence and brain myelination.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Animals, Suckling
  • Bile / analysis*
  • Deoxycholic Acid / analysis*
  • Deoxycholic Acid / deficiency
  • Feces / analysis*
  • Feeding Behavior*
  • Female
  • Lactation
  • Pheromones / analysis*
  • Pregnancy
  • Rats
  • Rats, Inbred Strains

Substances

  • Pheromones
  • Deoxycholic Acid