Busulphan lung in childhood

J Clin Pathol. 1981 May;34(5):495-500. doi: 10.1136/jcp.34.5.495.

Abstract

A child receiving busulphan treatment for adult-type chronic myeloid leukaemia responded well for four years before the onset of complications leading to "busulphan lung'. Pulmonary function tests (PFT) were useful in monitoring the development of this condition and we recommended regular PFT for patient receiving busulphan treatment.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Busulfan / adverse effects*
  • Busulfan / therapeutic use
  • Child, Preschool
  • Humans
  • Leukemia, Myeloid / drug therapy
  • Male
  • Microscopy, Electron
  • Pulmonary Alveoli / ultrastructure
  • Pulmonary Fibrosis / chemically induced*
  • Pulmonary Fibrosis / pathology
  • Respiratory Function Tests

Substances

  • Busulfan