Tamoxifen antiestrogens. A comparison of the activity, pharmacokinetics, and metabolic activation of the cis and trans isomers of tamoxifen

J Steroid Biochem. 1982 Jan;16(1):1-13. doi: 10.1016/0022-4731(82)90137-6.
No abstract available

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Animals
  • Binding, Competitive
  • Biotransformation
  • Estradiol / pharmacology
  • Female
  • Isomerism
  • Organ Size / drug effects
  • Peroxidases / metabolism
  • Rats
  • Receptors, Estrogen / metabolism
  • Tamoxifen / metabolism
  • Tamoxifen / pharmacology*
  • Uterus / drug effects*

Substances

  • Receptors, Estrogen
  • Tamoxifen
  • Estradiol
  • Peroxidases