Scalp hair, fingernail and water samples collected from different parts of Egypt are analysed by atomic absorption spectrophotometry and neutron activation analysis. The results for hair show minimum variation of Zn among different regions; a relatively well-controlled dispersion of values (maximum to minimum less than 2) for Co, Fe, Mn and Se; an overall inter-regional variation of factors of 7, 10, 6, 4 and 6 for the elements Ag, Cd, Cs, Sc and W, respectively; a steady decline in the concentration of Sc from south (Aswan) to north (Alexandria). The findings for nail show a steady decline in the concentration of Fe and Sc from south (Aswan) to north (Alexandria); elevated levels of Cd in samples from Aswan area; and regional variations extending up to factors of 6.5, 3.6, 4.7, 5.9, 4.4, 4.5 and 1.9 for Co, Cr, Cs, Mn, Mo, W and Zn, respectively. No unified relationship is observed between the elemental compositions of hair and nail. For Cr, Cs, Fe, Sb and Sc mean values for hair are lower than in nails. Among the remaining elements the ratio nail/hair is less than 1 for Ag in Assiut, El Kharga and Alexandria, for Cd in all of the areas with the exception of Aswan, for Co, Mn and Mo in Cairo, for Zn in Cairo and Alexandria, and for W in Alexandria. The data for water samples reflect highest concentration of all the measured elements in the Mediterranean sea; a steady increase of the concentration of Cu in drinking water from south to north and for Nile water a similar trend for Ca and Mg; and elevated concentrations of Sb and Mn in river water. No distinct trend for the interrelationship between water and tissue elemental concentrations could be established for the regions around Cairo, Aswan and Alexandria.