Mapping of the X-linked immune deficiency mutation (xid) of CBA/N mice

J Immunol. 1980 Apr;124(4):1875-7.

Abstract

CBA/N mice carry a recessive mutation at the X-linked immune deficiency (xid) locus that precludes their response to certain thymus-independent (TI) antigens. We have determined that xid is situated on the X-chromosome between the genes Ta (tabby) and Hyp (hypophosphatemia), genetic distances being Ta-6.6 +/- 1.8-xid-12.2 +/- 2.3-Hyp.

MeSH terms

  • Animals
  • Chromosome Mapping*
  • Crosses, Genetic
  • Female
  • Gene Frequency
  • Immunologic Deficiency Syndromes / genetics*
  • Male
  • Mice
  • Mice, Inbred CBA / genetics*
  • Mutation*
  • Recombination, Genetic
  • X Chromosome / immunology