Home care, sometimes in the technical form of home hospitalization, is essential in caring for patients with cystic fibrosis, both to avoid separating the children from their environment and rupturing their life rhythms, but also to reduce the risk of hospital contamination. Home care requires an evaluation of the disease status, good patient and family information and good coordination between the different partners. Thus the reduction in hospitalization greatly improves the quality of life in patients with cystic fibrosis.