The laparoscopic transperitoneal adrenalectomy combines the advantages of the conventional transperitoneal approach with the well known advantages of minimally invasive surgery. The positive personal experience in 5 patients and the results of the literature are reported. According to these data we are dealing with a safe procedure requiring an acceptable operating time, little postoperative pain of short duration, fast recovery and a short postoperative in-hospital stay. Indications are benign non-hormone- as well as hormone-producing adrenal lesions. Until now there are no definitive size limitations. Malignant tumors should continue to be operated conventionally.