A pilot study of cisplatin based combination chemotherapy in gastric cancer

A McDonald; M Harding; L McNulty; D Cunningham; M Soukop

doi:10.1016/s0936-6555(05)80901-x

A pilot study of cisplatin based combination chemotherapy in gastric cancer

Clin Oncol (R Coll Radiol). 1993;5(5):284-5. doi: 10.1016/s0936-6555(05)80901-x.

Authors

A McDonald¹, M Harding, L McNulty, D Cunningham, M Soukop

Affiliation

¹ Department of Medical Oncology, Glasgow Royal Infirmary, UK.

PMID: 8305335
DOI: 10.1016/s0936-6555(05)80901-x

Abstract

A pilot study evaluating cisplatin in combination with 5-fluorouracil, methotrexate and epirubicin in advanced gastric cancer was initiated. Twenty patients were treated, eight with locally advanced or recurrent disease, and 12 with metastatic gastric cancer. The overall response rate was 35% (95% confidence interval 14%-56%).

MeSH terms

Adult
Aged
Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
Cisplatin / administration & dosage*
Epirubicin / administration & dosage
Fluorouracil / administration & dosage
Humans
Methotrexate / administration & dosage
Middle Aged
Pilot Projects
Remission Induction
Stomach Neoplasms / drug therapy*

Substances

Epirubicin
Cisplatin
Fluorouracil
Methotrexate