Abstract
The 10-year survival rate for medullary carcinoma of the thyroid (MCT) is 50%; thus, good tumor-seeking radiopharmaceuticals are needed to localize foci of recurrence and metastasis during follow-up. Two patients with metastatic MCT were studied with Tl-201, I-131 MIBG, Tc-99m (V)-DMSA, and Tc-99m MIBI. A SPECT study with the latter agent allowed the visualization and precise localization of a metastatic mediastinal lymph node. More studies need to be done to evaluate the role of Tc-99m MIBI in the detection of recurrence and metastases of MCT.
MeSH terms
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Adult
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Aged
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Carcinoma, Medullary / diagnostic imaging*
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Carcinoma, Medullary / secondary
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Evaluation Studies as Topic
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Female
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Humans
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Lymphatic Metastasis / diagnostic imaging
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Male
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Neoplasm Recurrence, Local / diagnostic imaging
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Organotechnetium Compounds
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Succimer
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Technetium Tc 99m Dimercaptosuccinic Acid
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Technetium Tc 99m Sestamibi*
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Thyroid Neoplasms / diagnostic imaging*
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Tomography, Emission-Computed, Single-Photon
Substances
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Organotechnetium Compounds
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Technetium Tc 99m Dimercaptosuccinic Acid
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Technetium Tc 99m Sestamibi
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Succimer