Leflunomide, a novel immunomodulatory agent: in vitro analyses of the mechanism of immunosuppression

Transplant Proc. 1993 Feb;25(1 Pt 1):747-9.
No abstract available

MeSH terms

  • Cells, Cultured
  • Cyclosporine / pharmacology
  • Dose-Response Relationship, Drug
  • Drug Interactions
  • Humans
  • Immunosuppression Therapy
  • Immunosuppressive Agents / pharmacology*
  • Isoxazoles / pharmacology*
  • Leflunomide
  • Lymphocyte Activation / drug effects
  • Polyenes / pharmacology
  • Sirolimus
  • T-Lymphocytes / drug effects
  • T-Lymphocytes / immunology*
  • T-Lymphocytes / radiation effects
  • Thymidine / metabolism
  • Tritium

Substances

  • Immunosuppressive Agents
  • Isoxazoles
  • Polyenes
  • Tritium
  • Cyclosporine
  • Leflunomide
  • Thymidine
  • Sirolimus