Assignment of the human prosaposin gene (PSAP) to 10q22.1 by fluorescence in situ hybridization. Giraffidae, okapi (Okapiajohnstoni), and giraffe (Giraffa camelopardalis): evidence for ancestral telomeres at the okapi polymorphic rob (4;26) fusion site

I Bar-Am; L Avivi; M Horowitz

doi:10.1159/000134212

Assignment of the human prosaposin gene (PSAP) to 10q22.1 by fluorescence in situ hybridization. Giraffidae, okapi (Okapiajohnstoni), and giraffe (Giraffa camelopardalis): evidence for ancestral telomeres at the okapi polymorphic rob (4;26) fusion site

Cytogenet Cell Genet. 1996;72(4):316-8. doi: 10.1159/000134212.

Authors

I Bar-Am¹, L Avivi, M Horowitz

Affiliation

¹ Department of Human Genetics, Sackler Faculty of Medicine, Tel Aviv University, Israel.

PMID: 8641138
DOI: 10.1159/000134212

Abstract

The human prosaposin gene (PSAP) was previously localized to 10q21-->q22 by isotopic in situ hybridization using a human prosaposin cDNA as a probe. The present study, using fluorescence in situ hybridization with a mouse genomic prosaposin fragment as probe, confirms the localization of PSAP and precisely maps it to band 10q22.1.

MeSH terms

Animals
Chromosome Mapping
Chromosomes, Human, Pair 10 / genetics*
Chromosomes, Human, Pair 10 / ultrastructure
DNA Probes
Glycoproteins / genetics*
Humans
In Situ Hybridization, Fluorescence
Mice
Protein Precursors / genetics*
Saposins

Substances

DNA Probes
Glycoproteins
PSAP protein, human
Protein Precursors
Psap protein, mouse
Saposins