Twenty-eight fetal wrists aged 5 to 21 weeks gestation were examined histologically to assess ulnar variance. There was a trend from ulna negative to ulna neutral among this population. Of 10 wrists in group I (5-8 weeks gestation), 8 were ulna negative and 2 were ulna neutral. Of nine wrists in group II (11-13 weeks gestation), three were ulna negative and six were ulna neutral. Of nine wrists in group III (18-21 weeks gestation), two were ulna negative and seven were ulna neutral. Overall, 13 embryos demonstrated an ulna negative variance; the remainder had ulna neutral variance. These results are significantly different than the incidence of ulnar variance in adults. With growth, factors must occur that change this fetal relationship of radius to ulna.