Abstract
The correct concentration and vehicle for patch testing with corticosteroids is in many instances not known. The results of this study suggest that 1% in ethanol should be the initial choice, unless it can be shown that petrolatum as a vehicle is as sensitive (tixocortol pivalate and budesonide). We could find no evidence for the anti-inflammatory effects of corticosteroids inhibiting the patch test at higher concentrations. Using ethanol as the vehicle resulted in reactions developing at earlier time points than with petrolatum.
MeSH terms
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Administration, Topical
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Anti-Inflammatory Agents / adverse effects*
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Budesonide
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Dermatitis, Allergic Contact / diagnosis*
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Dermatitis, Allergic Contact / etiology
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Dermatologic Agents / adverse effects*
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Drug Eruptions / diagnosis*
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Drug Eruptions / etiology
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Ethanol
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Humans
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Hydrocortisone / adverse effects
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Hydrocortisone / analogs & derivatives*
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Patch Tests / methods*
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Petrolatum
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Pharmaceutical Vehicles*
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Pregnenediones / adverse effects*
Substances
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Anti-Inflammatory Agents
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Dermatologic Agents
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Pharmaceutical Vehicles
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Pregnenediones
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hydrocortisone-17-butyrate
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Ethanol
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Budesonide
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tixocortol pivalate
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Petrolatum
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Hydrocortisone