Peripheral facial palsy: antibody levels to Borrelia in serum and CSF

Clin Otolaryngol Allied Sci. 1993 Oct;18(5):419-22. doi: 10.1111/j.1365-2273.1993.tb00605.x.

Abstract

Serum antibodies to Borrelia burgdorferi antigen were determined in 71 consecutive patients with an acute peripheral facial palsy. The study was conducted for one year in a south western coastal region in Sweden. Twenty-one per cent of the patients had significantly elevated serum levels of antibodies to Borrelia burgdorferi antigen. CSF was examined in 13 of the sero-positive patients. In three of these (23%) Borrelia antibodies were found. Another five patients had a pathological protein and cell pattern in the CSF. No seasonal differences were observed. Four of the sero-positive patients had a long-term history of dermatological neurological manifestations compatible with the late third stage of the disease.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Antibodies
  • Borrelia Infections / blood*
  • Borrelia Infections / cerebrospinal fluid*
  • Borrelia burgdorferi Group / isolation & purification*
  • Child
  • Child, Preschool
  • Facial Paralysis / blood*
  • Facial Paralysis / cerebrospinal fluid*
  • Female
  • Humans
  • Immunoglobulin G / immunology
  • Male
  • Middle Aged
  • Prospective Studies
  • Seasons

Substances

  • Antibodies
  • Immunoglobulin G