Background: Pretreatment serum values of S-100 and NSE were compared in patients with malignant melanoma.
Materials and methods: Pretreatment serum levels of patients with malignant melanoma were analysed for stage of disease and survival.
Results: S-100 pretreatment serum values seem highly specific, but have low sensitivity.
Conclusion: Further evaluation is needed with an assay with improved sensitivity.