Although transesophageal echocardiography is considered a generally safe procedure, occasional complications have been reported. Serious esophageal trauma and Mallory Weiss tear have been described, as well as post-transesophageal echocardiography dysphagia. However, to our knowledge, upper airway and esophageal obstruction have not been previously cited. A case of upper airway obstruction resulting from a transesophageal echocardiography procedure is herein detailed.