Aims and background: Adult granulosa cell tumor has a low malignant potential but requires an extensive follow-up of more than 5 years to accurately assess tumor activity. The aim of the present study was to evaluate the clinical characteristics, the treatment and the outcome of this rare ovarian tumor.
Study design: A retrospective review of 35 cases treated at primary onset of disease during a 23-year period from 1971 to 1993.
Results: The disease-free survival rate for stages IA-B-C at 5 and 10 years was 90% and 84%, respectively; for stages III-IV the 5-year freedom from progression rate was 16%.
Conclusions: The most important prognostic factor appears to be the extent of tumor involvement outside of the ovary.