Ureteral double-J stents are currently being used widely in numerous urologic indications. Side effects are infrequent and usually related to the act of insertion per se. Complications with long-term indwelling stents are mainly due to stent incrustation and more rarely to spontaneous breakage. We report 3 cases of stent multiple fragmentation after and indwelling period superior to 22 months without evidence of stent incrustation. We reviewed the literature and analyzed the different etiologic factors that are thought to be involved. We believe that radiologic control post-insertion and stent substitution after an indwelling period of three months are mandatory.