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Polar amino acid-rich sequences bind to polyglutamine tracts.
Imafuku I, Waragai M, Takeuchi S, Kanazawa I, Kawabata M, Mouradian MM, Okazawa H. Imafuku I, et al. Among authors: waragai m. Biochem Biophys Res Commun. 1998 Dec 9;253(1):16-20. doi: 10.1006/bbrc.1998.9725. Biochem Biophys Res Commun. 1998. PMID: 9875212
Interaction between mutant ataxin-1 and PQBP-1 affects transcription and cell death.
Okazawa H, Rich T, Chang A, Lin X, Waragai M, Kajikawa M, Enokido Y, Komuro A, Kato S, Shibata M, Hatanaka H, Mouradian MM, Sudol M, Kanazawa I. Okazawa H, et al. Among authors: waragai m. Neuron. 2002 May 30;34(5):701-13. doi: 10.1016/s0896-6273(02)00697-9. Neuron. 2002. PMID: 12062018 Free article.
Presenilin 1 binds to amyloid precursor protein directly.
Waragai M, Imafuku I, Takeuchi S, Kanazawa I, Oyama F, Udagawa Y, Kawabata M, Okazawa H. Waragai M, et al. Biochem Biophys Res Commun. 1997 Oct 20;239(2):480-2. doi: 10.1006/bbrc.1997.7488. Biochem Biophys Res Commun. 1997. PMID: 9344855
JNK activation is associated with intracellular beta-amyloid accumulation.
Shoji M, Iwakami N, Takeuchi S, Waragai M, Suzuki M, Kanazawa I, Lippa CF, Ono S, Okazawa H. Shoji M, et al. Among authors: waragai m. Brain Res Mol Brain Res. 2000 Dec 28;85(1-2):221-33. doi: 10.1016/s0169-328x(00)00245-x. Brain Res Mol Brain Res. 2000. PMID: 11146125
DNA damage in embryonic neural stem cell determines FTLDs' fate via early-stage neuronal necrosis.
Homma H, Tanaka H, Jin M, Jin X, Huang Y, Yoshioka Y, Bertens CJ, Tsumaki K, Kondo K, Shiwaku H, Tagawa K, Akatsu H, Atsuta N, Katsuno M, Furukawa K, Ishiki A, Waragai M, Ohtomo G, Iwata A, Yokota T, Inoue H, Arai H, Sobue G, Sone M, Fujita K, Okazawa H. Homma H, et al. Among authors: waragai m. Life Sci Alliance. 2021 Jun 15;4(7):e202101022. doi: 10.26508/lsa.202101022. Print 2021 Jul. Life Sci Alliance. 2021. PMID: 34130995 Free PMC article.
YAP-dependent necrosis occurs in early stages of Alzheimer's disease and regulates mouse model pathology.
Tanaka H, Homma H, Fujita K, Kondo K, Yamada S, Jin X, Waragai M, Ohtomo G, Iwata A, Tagawa K, Atsuta N, Katsuno M, Tomita N, Furukawa K, Saito Y, Saito T, Ichise A, Shibata S, Arai H, Saido T, Sudol M, Muramatsu SI, Okano H, Mufson EJ, Sobue G, Murayama S, Okazawa H. Tanaka H, et al. Among authors: waragai m. Nat Commun. 2020 Jan 24;11(1):507. doi: 10.1038/s41467-020-14353-6. Nat Commun. 2020. PMID: 31980612 Free PMC article.
111 results