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A phase I clinical and pharmacokinetic study of the angiogenesis inhibitor, tecogalan sodium.
Eckhardt SG, Burris HA, Eckardt JR, Weiss G, Rodriguez G, Rothenberg M, Rinaldi D, Barrington R, Kuhn JG, Masuo K, Sudo K, Atsumi R, Oguma T, Higashi L, Fields S, Smetzer L, Von Hoff DD. Eckhardt SG, et al. Among authors: barrington r. Ann Oncol. 1996 Jul;7(5):491-6. doi: 10.1093/oxfordjournals.annonc.a010638. Ann Oncol. 1996. PMID: 8839904 Free article. Clinical Trial.
A farnesyltransferase inhibitor induces tumor regression in transgenic mice harboring multiple oncogenic mutations by mediating alterations in both cell cycle control and apoptosis.
Barrington RE, Subler MA, Rands E, Omer CA, Miller PJ, Hundley JE, Koester SK, Troyer DA, Bearss DJ, Conner MW, Gibbs JB, Hamilton K, Koblan KS, Mosser SD, O'Neill TJ, Schaber MD, Senderak ET, Windle JJ, Oliff A, Kohl NE. Barrington RE, et al. Mol Cell Biol. 1998 Jan;18(1):85-92. doi: 10.1128/MCB.18.1.85. Mol Cell Biol. 1998. PMID: 9418856 Free PMC article.
Amyloid-β and caspase-1 are indicators of sepsis and organ injury.
Tuckey AN, Brandon A, Eslaamizaad Y, Siddiqui W, Nawaz T, Clarke C, Sutherland E, Williams V, Spadafora D, Barrington RA, Alvarez DF, Mulekar MS, Simmons JD, Fouty BW, Audia JP. Tuckey AN, et al. Among authors: barrington ra. ERJ Open Res. 2024 Feb 26;10(1):00572-2023. doi: 10.1183/23120541.00572-2023. eCollection 2024 Jan. ERJ Open Res. 2024. PMID: 38410714 Free PMC article.
A mouse model of Zhu-Tokita-Takenouchi-Kim syndrome reveals indispensable SON functions in organ development and hematopoiesis.
Vukadin L, Park B, Mohamed M, Li H, Elkholy A, Torrelli-Diljohn A, Kim JH, Jeong K, Murphy JM, Harvey CA, Dunlap S, Gehrs L, Lee H, Kim HG, Sah JP, Lee SN, Stanford D, Barrington RA, Foote JB, Sorace AG, Welner RS, Hildreth BE 3rd, Lim SS, Ahn EE. Vukadin L, et al. Among authors: barrington ra. JCI Insight. 2024 Mar 8;9(5):e175053. doi: 10.1172/jci.insight.175053. JCI Insight. 2024. PMID: 38290089 Free PMC article.
A mouse model of ZTTK syndrome reveals indispensable SON functions in organ development and hematopoiesis.
Vukadin L, Park B, Mohamed M, Li H, Elkholy A, Torrelli-Diljohn A, Kim JH, Jeong K, Murphy JM, Harvey CA, Dunlap S, Gehrs L, Lee H, Kim HG, Lee SN, Stanford D, Barrington RA, Foote JB, Sorace AG, Welner RS, Hildreth BE 3rd, Lim SS, Ahn EE. Vukadin L, et al. Among authors: barrington ra. bioRxiv [Preprint]. 2023 Nov 19:2023.11.19.567732. doi: 10.1101/2023.11.19.567732. bioRxiv. 2023. PMID: 38014320 Free PMC article. Updated. Preprint.
Gamma secretase activating protein promotes end-organ dysfunction after bacterial pneumonia.
Gwin MS, Alexeyev MF, Geurts AM, Lee JY, Zhou C, Yang XM, Cohen MV, Downey JM, Barrington RA, Spadafora D, Audia JP, Frank DW, Voth S, Pastukh VV, Bell J, Ayers L, Tambe DT, Nelson AR, Balczon R, Lin MT, Stevens T. Gwin MS, et al. Among authors: barrington ra. Am J Physiol Lung Cell Mol Physiol. 2023 Aug 1;325(2):L174-L189. doi: 10.1152/ajplung.00018.2023. Epub 2023 Jun 27. Am J Physiol Lung Cell Mol Physiol. 2023. PMID: 37366533 Free PMC article.
70 results