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Arginase I production in the tumor microenvironment by mature myeloid cells inhibits T-cell receptor expression and antigen-specific T-cell responses.
Rodriguez PC, Quiceno DG, Zabaleta J, Ortiz B, Zea AH, Piazuelo MB, Delgado A, Correa P, Brayer J, Sotomayor EM, Antonia S, Ochoa JB, Ochoa AC. Rodriguez PC, et al. Among authors: ochoa ac, ochoa jb. Cancer Res. 2004 Aug 15;64(16):5839-49. doi: 10.1158/0008-5472.CAN-04-0465. Cancer Res. 2004. PMID: 15313928
Mechanisms of tumor evasion from the immune response.
Rodríguez PC, Zea AH, Ochoa AC. Rodríguez PC, et al. Among authors: ochoa ac. Cancer Chemother Biol Response Modif. 2003;21:351-64. doi: 10.1016/s0921-4410(03)21018-8. Cancer Chemother Biol Response Modif. 2003. PMID: 15338755 Review.
A phase I randomized study of subcutaneous adjuvant IL-2 in combination with an autologous tumor vaccine in patients with advanced renal cell carcinoma.
Fenton RG, Steis RG, Madara K, Zea AH, Ochoa AC, Janik JE, Smith JW 2nd, Gause BL, Sharfman WH, Urba WJ, Hanna MG, DeJager RL, Coyne MX, Crouch RD, Gray P, Beveridge J, Creekmore SP, Holmlund J, Curti BD, Sznol M, Longo DL. Fenton RG, et al. Among authors: ochoa ac. J Immunother Emphasis Tumor Immunol. 1996 Sep;19(5):364-74. doi: 10.1097/00002371-199609000-00006. J Immunother Emphasis Tumor Immunol. 1996. PMID: 8941876 Clinical Trial.
136 results