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Guided selection of a pan carcinoma specific antibody reveals similar binding characteristics yet structural divergence between the original murine antibody and its human equivalent.
J Mol Biol. 2000 Feb 25;296(3):833-49. doi: 10.1006/jmbi.2000.3512.
J Mol Biol. 2000.
PMID: 10677285
Antibody variable regions: toward a unified modeling method.
Whitelegg N, Rees AR.
Whitelegg N, et al.
Methods Mol Biol. 2004;248:51-91. doi: 10.1385/1-59259-666-5:51.
Methods Mol Biol. 2004.
PMID: 14970491
No abstract available.
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WAM: an improved algorithm for modelling antibodies on the WEB.
Whitelegg NR, Rees AR.
Whitelegg NR, et al.
Protein Eng. 2000 Dec;13(12):819-24. doi: 10.1093/protein/13.12.819.
Protein Eng. 2000.
PMID: 11239080
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A strategy for mapping and neutralizing conformational immunogenic sites on protein therapeutics.
Spencer DI, Robson L, Purdy D, Whitelegg NR, Michael NP, Bhatia J, Sharma SK, Rees AR, Minton NP, Begent RH, Chester KA.
Spencer DI, et al. Among authors: whitelegg nr.
Proteomics. 2002 Mar;2(3):271-9. doi: 10.1002/1615-9861(200203)2:3<271::aid-prot271>3.0.co;2-w.
Proteomics. 2002.
PMID: 11921443
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