Goldstein LE - Search Results

1

Evidence that the beta-amyloid plaques of Alzheimer's disease represent the redox-silencing and entombment of abeta by zinc.

Cuajungco MP, Goldstein LE, Nunomura A, Smith MA, Lim JT, Atwood CS, Huang X, Farrag YW, Perry G, Bush AI. Cuajungco MP, et al. Among authors: goldstein le. J Biol Chem. 2000 Jun 30;275(26):19439-42. doi: 10.1074/jbc.C000165200. J Biol Chem. 2000. PMID: 10801774 Free article.

2

The A beta peptide of Alzheimer's disease directly produces hydrogen peroxide through metal ion reduction.

Huang X, Atwood CS, Hartshorn MA, Multhaup G, Goldstein LE, Scarpa RC, Cuajungco MP, Gray DN, Lim J, Moir RD, Tanzi RE, Bush AI. Huang X, et al. Among authors: goldstein le. Biochemistry. 1999 Jun 15;38(24):7609-16. doi: 10.1021/bi990438f. Biochemistry. 1999. PMID: 10386999

3

Cu(II) potentiation of alzheimer abeta neurotoxicity. Correlation with cell-free hydrogen peroxide production and metal reduction.

Huang X, Cuajungco MP, Atwood CS, Hartshorn MA, Tyndall JD, Hanson GR, Stokes KC, Leopold M, Multhaup G, Goldstein LE, Scarpa RC, Saunders AJ, Lim J, Moir RD, Glabe C, Bowden EF, Masters CL, Fairlie DP, Tanzi RE, Bush AI. Huang X, et al. Among authors: goldstein le. J Biol Chem. 1999 Dec 24;274(52):37111-6. doi: 10.1074/jbc.274.52.37111. J Biol Chem. 1999. PMID: 10601271 Free article.

4

3-Hydroxykynurenine and 3-hydroxyanthranilic acid generate hydrogen peroxide and promote alpha-crystallin cross-linking by metal ion reduction.

Goldstein LE, Leopold MC, Huang X, Atwood CS, Saunders AJ, Hartshorn M, Lim JT, Faget KY, Muffat JA, Scarpa RC, Chylack LT Jr, Bowden EF, Tanzi RE, Bush AI. Goldstein LE, et al. Biochemistry. 2000 Jun 20;39(24):7266-75. doi: 10.1021/bi992997s. Biochemistry. 2000. PMID: 10852726

5

Specific metal-catalysed protein oxidation reactions in chronic degenerative disorders of ageing: focus on Alzheimer's disease and age-related cataracts.

Bush AI, Goldstein LE. Bush AI, et al. Among authors: goldstein le. Novartis Found Symp. 2001;235:26-38; discussion 38-43. doi: 10.1002/0470868694.ch4. Novartis Found Symp. 2001. PMID: 11280030 Review.

6

Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice.

Cherny RA, Atwood CS, Xilinas ME, Gray DN, Jones WD, McLean CA, Barnham KJ, Volitakis I, Fraser FW, Kim Y, Huang X, Goldstein LE, Moir RD, Lim JT, Beyreuther K, Zheng H, Tanzi RE, Masters CL, Bush AI. Cherny RA, et al. Among authors: goldstein le. Neuron. 2001 Jun;30(3):665-76. doi: 10.1016/s0896-6273(01)00317-8. Neuron. 2001. PMID: 11430801 Free article.

7

Could Abeta and AbetaPP be Antioxidants?

Bush AI, Atwood CS, Goldstein LE, Huang X, Rogers J. Bush AI, et al. Among authors: goldstein le. J Alzheimers Dis. 2000 Jun;2(2):83-84. doi: 10.3233/jad-2000-2203. J Alzheimers Dis. 2000. PMID: 12214093 No abstract available.

8

Cytosolic beta-amyloid deposition and supranuclear cataracts in lenses from people with Alzheimer's disease.

Goldstein LE, Muffat JA, Cherny RA, Moir RD, Ericsson MH, Huang X, Mavros C, Coccia JA, Faget KY, Fitch KA, Masters CL, Tanzi RE, Chylack LT Jr, Bush AI. Goldstein LE, et al. Lancet. 2003 Apr 12;361(9365):1258-65. doi: 10.1016/S0140-6736(03)12981-9. Lancet. 2003. PMID: 12699953

9

RNA therapeutics directed to the non coding regions of APP mRNA, in vivo anti-amyloid efficacy of paroxetine, erythromycin, and N-acetyl cysteine.

Tucker S, Ahl M, Cho HH, Bandyopadhyay S, Cuny GD, Bush AI, Goldstein LE, Westaway D, Huang X, Rogers JT. Tucker S, et al. Among authors: goldstein le. Curr Alzheimer Res. 2006 Jul;3(3):221-7. doi: 10.2174/156720506777632835. Curr Alzheimer Res. 2006. PMID: 16842099

10

The Alzheimer's disease-associated amyloid beta-protein is an antimicrobial peptide.

Soscia SJ, Kirby JE, Washicosky KJ, Tucker SM, Ingelsson M, Hyman B, Burton MA, Goldstein LE, Duong S, Tanzi RE, Moir RD. Soscia SJ, et al. Among authors: goldstein le. PLoS One. 2010 Mar 3;5(3):e9505. doi: 10.1371/journal.pone.0009505. PLoS One. 2010. PMID: 20209079 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

86 results

Search Page