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Animal model of mucosally transmitted human immunodeficiency virus type 1 disease: intravaginal and oral deposition of simian/human immunodeficiency virus in macaques results in systemic infection, elimination of CD4+ T cells, and AIDS.
Joag SV, Adany I, Li Z, Foresman L, Pinson DM, Wang C, Stephens EB, Raghavan R, Narayan O. Joag SV, et al. Among authors: li z. J Virol. 1997 May;71(5):4016-23. doi: 10.1128/JVI.71.5.4016-4023.1997. J Virol. 1997. PMID: 9094679 Free PMC article.
We derived a SHIV that caused CD4+ cell loss and AIDS in pig-tailed macaques (S. V. Joag, Z. Li, L. Foresman, E. B. Stephens, L. J. Zhao, I. Adany, D. M. ...
We derived a SHIV that caused CD4+ cell loss and AIDS in pig-tailed macaques (S. V. Joag, Z. Li, L. Foresman, E. B. Stephens, …
A cell-free stock of simian-human immunodeficiency virus that causes AIDS in pig-tailed macaques has a limited number of amino acid substitutions in both SIVmac and HIV-1 regions of the genome and has offered cytotropism.
Stephens EB, Mukherjee S, Sahni M, Zhuge W, Raghavan R, Singh DK, Leung K, Atkinson B, Li Z, Joag SV, Liu ZQ, Narayan O. Stephens EB, et al. Among authors: li z. Virology. 1997 May 12;231(2):313-21. doi: 10.1006/viro.1997.8534. Virology. 1997. PMID: 9168893 Free article.
Simian-human immunodeficiency virus (SHIV) containing the nef/long terminal repeat region of the highly virulent SIVsmmPBj14 causes PBj-like activation of cultured resting peripheral blood mononuclear cells, but the chimera showed No increase in virulence.
Stephens EB, Mukherjee S, Liu ZQ, Sheffer D, Lamb-Wharton R, Leung K, Zhuge W, Joag SV, Li Z, Foresman L, Adany I, Narayan O. Stephens EB, et al. Among authors: li z. J Virol. 1998 Jun;72(6):5207-14. doi: 10.1128/JVI.72.6.5207-5214.1998. J Virol. 1998. PMID: 9573293 Free PMC article.
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