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Transgenic mouse models of Alzheimer's disease.
Janus C, Westaway D. Janus C, et al. Physiol Behav. 2001 Aug;73(5):873-86. doi: 10.1016/s0031-9384(01)00524-8. Physiol Behav. 2001. PMID: 11566220 Review.
New developments in animal models of Alzheimer's disease.
Janus C, Phinney AL, Chishti MA, Westaway D. Janus C, et al. Curr Neurol Neurosci Rep. 2001 Sep;1(5):451-7. doi: 10.1007/s11910-001-0105-8. Curr Neurol Neurosci Rep. 2001. PMID: 11898556 Review.
Therapeutically effective antibodies against amyloid-beta peptide target amyloid-beta residues 4-10 and inhibit cytotoxicity and fibrillogenesis.
McLaurin J, Cecal R, Kierstead ME, Tian X, Phinney AL, Manea M, French JE, Lambermon MH, Darabie AA, Brown ME, Janus C, Chishti MA, Horne P, Westaway D, Fraser PE, Mount HT, Przybylski M, St George-Hyslop P. McLaurin J, et al. Among authors: janus c. Nat Med. 2002 Nov;8(11):1263-9. doi: 10.1038/nm790. Epub 2002 Oct 15. Nat Med. 2002. PMID: 12379850
Presenilin mutations associated with Alzheimer disease cause defective intracellular trafficking of beta-catenin, a component of the presenilin protein complex.
Nishimura M, Yu G, Levesque G, Zhang DM, Ruel L, Chen F, Milman P, Holmes E, Liang Y, Kawarai T, Jo E, Supala A, Rogaeva E, Xu DM, Janus C, Levesque L, Bi Q, Duthie M, Rozmahel R, Mattila K, Lannfelt L, Westaway D, Mount HT, Woodgett J, St George-Hyslop P, et al. Nishimura M, et al. Among authors: janus c. Nat Med. 1999 Feb;5(2):164-9. doi: 10.1038/5526. Nat Med. 1999. PMID: 9930863
Transgenic mouse models of Alzheimer's disease.
Janus C, Chishti MA, Westaway D. Janus C, et al. Biochim Biophys Acta. 2000 Jul 26;1502(1):63-75. doi: 10.1016/s0925-4439(00)00033-8. Biochim Biophys Acta. 2000. PMID: 10899432 Free article. Review. No abstract available.
Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and betaAPP processing.
Yu G, Nishimura M, Arawaka S, Levitan D, Zhang L, Tandon A, Song YQ, Rogaeva E, Chen F, Kawarai T, Supala A, Levesque L, Yu H, Yang DS, Holmes E, Milman P, Liang Y, Zhang DM, Xu DH, Sato C, Rogaev E, Smith M, Janus C, Zhang Y, Aebersold R, Farrer LS, Sorbi S, Bruni A, Fraser P, St George-Hyslop P. Yu G, et al. Among authors: janus c. Nature. 2000 Sep 7;407(6800):48-54. doi: 10.1038/35024009. Nature. 2000. PMID: 10993067
214 results