Nixon RA - Search Results

1

A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease.

Janus C, Pearson J, McLaurin J, Mathews PM, Jiang Y, Schmidt SD, Chishti MA, Horne P, Heslin D, French J, Mount HT, Nixon RA, Mercken M, Bergeron C, Fraser PE, St George-Hyslop P, Westaway D. Janus C, et al. Among authors: nixon ra. Nature. 2000 Dec 21-28;408(6815):979-82. doi: 10.1038/35050110. Nature. 2000. PMID: 11140685

2

Differential sensitivity to proteolysis by brain calpain of adult human tau, fetal human tau and PHF-tau.

Mercken M, Grynspan F, Nixon RA. Mercken M, et al. Among authors: nixon ra. FEBS Lett. 1995 Jul 10;368(1):10-4. doi: 10.1016/0014-5793(95)00590-6. FEBS Lett. 1995. PMID: 7615058 Free article.

3

Developmental expression of wild-type and mutant presenilin-1 in hippocampal neurons from transgenic mice: evidence for novel species-specific properties of human presenilin-1.

Lévesque L, Annaert W, Craessaerts K, Mathews PM, Seeger M, Nixon RA, Van Leuven F, Gandy S, Westaway D, St George-Hyslop P, De Strooper B, Fraser PE. Lévesque L, et al. Among authors: nixon ra. Mol Med. 1999 Aug;5(8):542-54. Mol Med. 1999. PMID: 10501657 Free PMC article.

4

The endosomal-lysosomal system of neurons in Alzheimer's disease pathogenesis: a review.

Nixon RA, Cataldo AM, Mathews PM. Nixon RA, et al. Neurochem Res. 2000 Oct;25(9-10):1161-72. doi: 10.1023/a:1007675508413. Neurochem Res. 2000. PMID: 11059790 Review.

5

Brain expression of presenilins in sporadic and early-onset, familial Alzheimer's disease.

Mathews PM, Cataldo AM, Kao BH, Rudnicki AG, Qin X, Yang JL, Jiang Y, Picciano M, Hulette C, Lippa CF, Bird TD, Nochlin D, Walter J, Haass C, Lévesque L, Fraser PE, Andreadis A, Nixon RA. Mathews PM, et al. Among authors: nixon ra. Mol Med. 2000 Oct;6(10):878-91. Mol Med. 2000. PMID: 11126202 Free PMC article.

6

Alzheimer's disease-related overexpression of the cation-dependent mannose 6-phosphate receptor increases Abeta secretion: role for altered lysosomal hydrolase distribution in beta-amyloidogenesis.

Mathews PM, Guerra CB, Jiang Y, Grbovic OM, Kao BH, Schmidt SD, Dinakar R, Mercken M, Hille-Rehfeld A, Rohrer J, Mehta P, Cataldo AM, Nixon RA. Mathews PM, et al. Among authors: nixon ra. J Biol Chem. 2002 Feb 15;277(7):5299-307. doi: 10.1074/jbc.M108161200. Epub 2001 Sep 10. J Biol Chem. 2002. PMID: 11551970 Free article.

7

Mature glycosylation and trafficking of nicastrin modulate its binding to presenilins.

Yang DS, Tandon A, Chen F, Yu G, Yu H, Arawaka S, Hasegawa H, Duthie M, Schmidt SD, Ramabhadran TV, Nixon RA, Mathews PM, Gandy SE, Mount HT, St George-Hyslop P, Fraser PE. Yang DS, et al. Among authors: nixon ra. J Biol Chem. 2002 Aug 2;277(31):28135-42. doi: 10.1074/jbc.M110871200. Epub 2002 May 24. J Biol Chem. 2002. PMID: 12032140 Free article.

8

Calpain activity regulates the cell surface distribution of amyloid precursor protein. Inhibition of calpains enhances endosomal generation of beta-cleaved C-terminal APP fragments.

Mathews PM, Jiang Y, Schmidt SD, Grbovic OM, Mercken M, Nixon RA. Mathews PM, et al. Among authors: nixon ra. J Biol Chem. 2002 Sep 27;277(39):36415-24. doi: 10.1074/jbc.M205208200. Epub 2002 Jun 26. J Biol Chem. 2002. PMID: 12087104 Free article.

9

The neuronal endosomal-lysosomal system in Alzheimer's disease.

Nixon RA, Mathews PM, Cataldo AM. Nixon RA, et al. J Alzheimers Dis. 2001 Feb;3(1):97-107. doi: 10.3233/jad-2001-3114. J Alzheimers Dis. 2001. PMID: 12214078

10

Alleles at the Nicastrin locus modify presenilin 1- deficiency phenotype.

Rozmahel R, Mount HT, Chen F, Nguyen V, Huang J, Erdebil S, Liauw J, Yu G, Hasegawa H, Gu Y, Song YQ, Schmidt SD, Nixon RA, Mathews PM, Bergeron C, Fraser P, Westaway D, St George-Hyslop P. Rozmahel R, et al. Among authors: nixon ra. Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):14452-7. doi: 10.1073/pnas.222413999. Epub 2002 Oct 18. Proc Natl Acad Sci U S A. 2002. PMID: 12388777 Free PMC article.

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