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In vitro and in vivo anticancer activities of synthetic macrocyclic ketone analogues of halichondrin B.
Cancer Res. 2001 Feb 1;61(3):1013-21.
Cancer Res. 2001.
PMID: 11221827
Structurally simplified macrolactone analogues of halichondrin B.
Seletsky BM, Wang Y, Hawkins LD, Palme MH, Habgood GJ, DiPietro LV, Towle MJ, Salvato KA, Wels BF, Aalfs KK, Kishi Y, Littlefield BA, Yu MJ.
Seletsky BM, et al. Among authors: palme mh.
Bioorg Med Chem Lett. 2004 Nov 15;14(22):5547-50. doi: 10.1016/j.bmcl.2004.08.068.
Bioorg Med Chem Lett. 2004.
PMID: 15482921
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Macrocyclic ketone analogues of halichondrin B.
Zheng W, Seletsky BM, Palme MH, Lydon PJ, Singer LA, Chase CE, Lemelin CA, Shen Y, Davis H, Tremblay L, Towle MJ, Salvato KA, Wels BF, Aalfs KK, Kishi Y, Littlefield BA, Yu MJ.
Zheng W, et al. Among authors: palme mh.
Bioorg Med Chem Lett. 2004 Nov 15;14(22):5551-4. doi: 10.1016/j.bmcl.2004.08.069.
Bioorg Med Chem Lett. 2004.
PMID: 15482922
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MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 4: Addressing the problem of poor stability due to photoisomerization of an acrylic acid moiety.
Nakayama K, Kuru N, Ohtsuka M, Yokomizo Y, Sakamoto A, Kawato H, Yoshida K, Ohta T, Hoshino K, Akimoto K, Itoh J, Ishida H, Cho A, Palme MH, Zhang JZ, Lee VJ, Watkins WJ.
Nakayama K, et al. Among authors: palme mh.
Bioorg Med Chem Lett. 2004 May 17;14(10):2493-7. doi: 10.1016/j.bmcl.2004.03.007.
Bioorg Med Chem Lett. 2004.
PMID: 15109639
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Synthesis and reactivity of a new glycosyl donor: O-(1-phenyltetrazol-5-yl) glucoside.
Palme M, Vasella A.
Palme M, et al.
Bioorg Med Chem. 1994 Nov;2(11):1169-77. doi: 10.1016/s0968-0896(00)82068-4.
Bioorg Med Chem. 1994.
PMID: 7757414
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MexAB-OprM specific efflux pump inhibitors in Pseudomonas aeruginosa. Part 3: Optimization of potency in the pyridopyrimidine series through the application of a pharmacophore model.
Nakayama K, Kawato H, Watanabe J, Ohtsuka M, Yoshida K, Yokomizo Y, Sakamoto A, Kuru N, Ohta T, Hoshino K, Yoshida K, Ishida H, Cho A, Palme MH, Zhang JZ, Lee VJ, Watkins WJ.
Nakayama K, et al. Among authors: palme mh.
Bioorg Med Chem Lett. 2004 Jan 19;14(2):475-9. doi: 10.1016/j.bmcl.2003.10.060.
Bioorg Med Chem Lett. 2004.
PMID: 14698185
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