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Page 1
Structurally simplified macrolactone analogues of halichondrin B.
Seletsky BM, Wang Y, Hawkins LD, Palme MH, Habgood GJ, DiPietro LV, Towle MJ, Salvato KA, Wels BF, Aalfs KK, Kishi Y, Littlefield BA, Yu MJ. Seletsky BM, et al. Among authors: wels bf. Bioorg Med Chem Lett. 2004 Nov 15;14(22):5547-50. doi: 10.1016/j.bmcl.2004.08.068. Bioorg Med Chem Lett. 2004. PMID: 15482921
Macrocyclic ketone analogues of halichondrin B.
Zheng W, Seletsky BM, Palme MH, Lydon PJ, Singer LA, Chase CE, Lemelin CA, Shen Y, Davis H, Tremblay L, Towle MJ, Salvato KA, Wels BF, Aalfs KK, Kishi Y, Littlefield BA, Yu MJ. Zheng W, et al. Among authors: wels bf. Bioorg Med Chem Lett. 2004 Nov 15;14(22):5551-4. doi: 10.1016/j.bmcl.2004.08.069. Bioorg Med Chem Lett. 2004. PMID: 15482922
Cetirizine and loratadine-based antihistamines with 5-lipoxygenase inhibitory activity.
Lewis TA, Young MA, Arrington MP, Bayless L, Cai X, Collart P, Eckman JB, Ellis JL, Ene DG, Libertine L, Nicolas JM, Scannell RT, Wels BF, Wenberg K, Wypij DM. Lewis TA, et al. Among authors: wels bf. Bioorg Med Chem Lett. 2004 Nov 15;14(22):5591-4. doi: 10.1016/j.bmcl.2004.08.060. Bioorg Med Chem Lett. 2004. PMID: 15482930
5-lipoxygenase inhibitors with histamine H(1) receptor antagonist activity.
Lewis TA, Bayless L, Eckman JB, Ellis JL, Grewal G, Libertine L, Marie Nicolas J, Scannell RT, Wels BF, Wenberg K, Wypij DM. Lewis TA, et al. Among authors: wels bf. Bioorg Med Chem Lett. 2004 May 3;14(9):2265-8. doi: 10.1016/j.bmcl.2004.02.005. Bioorg Med Chem Lett. 2004. PMID: 15081022
Novel dual acting molecules possessing 5-lipoxygenase enzyme inhibition and histamine H(1) receptor antagonist properties.
Scannell RT, Arrington MP, Bayless L, Cai X, Eckman JB, Eckert M, Ene DG, Ellis JL, Hussoin S, Latham GM, Lewis TA, Libertine L, Nicolas J, Selig WM, Schwartz CE, Wels BF, Wypij DM, Young MA, Zou D. Scannell RT, et al. Among authors: wels bf. Inflamm Res. 2004 Mar;53 Suppl 1:S33-4. doi: 10.1007/s00011-003-0315-4. Epub 2004 Mar 5. Inflamm Res. 2004. PMID: 15054606 No abstract available.
H1 antagonists: receptor affinity versus selectivity.
Gillard M, Christophe B, Wels B, Peck M, Massingham R, Chatelain P. Gillard M, et al. Inflamm Res. 2003 Apr;52 Suppl 1:S49-50. doi: 10.1007/s000110300050. Inflamm Res. 2003. PMID: 12755407 No abstract available.