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Immunization of metastatic breast cancer patients with a fully synthetic globo H conjugate: a phase I trial.
Gilewski T, Ragupathi G, Bhuta S, Williams LJ, Musselli C, Zhang XF, Bornmann WG, Spassova M, Bencsath KP, Panageas KS, Chin J, Hudis CA, Norton L, Houghton AN, Livingston PO, Danishefsky SJ. Gilewski T, et al. Among authors: zhang xf. Proc Natl Acad Sci U S A. 2001 Mar 13;98(6):3270-5. doi: 10.1073/pnas.051626298. Proc Natl Acad Sci U S A. 2001. PMID: 11248068 Free PMC article. Clinical Trial.
Polyclonal antibodies from patients immunized with a globo H-keyhole limpet hemocyanin vaccine: isolation, quantification, and characterization of immune responses by using totally synthetic immobilized tumor antigens.
Wang ZG, Williams LJ, Zhang XF, Zatorski A, Kudryashov V, Ragupathi G, Spassova M, Bornmann W, Slovin SF, Scher HI, Livingston PO, Lloyd KO, Danishefsky SJ. Wang ZG, et al. Among authors: zhang xf. Proc Natl Acad Sci U S A. 2000 Mar 14;97(6):2719-24. doi: 10.1073/pnas.97.6.2719. Proc Natl Acad Sci U S A. 2000. PMID: 10716997 Free PMC article.
A second generation synthesis of the MBr1 (globo-H) breast tumor antigen: new application of the n-pentenyl glycoside method for achieving complex carbohydrate protein linkages.
Allen JR, Allen JG, Zhang XF, Williams LJ, Zatorski A, Ragupathi G, Livingston PO, Danishefsky SJ. Allen JR, et al. Among authors: zhang xf. Chemistry. 2000 Apr 14;6(8):1366-75. doi: 10.1002/(sici)1521-3765(20000417)6:8<1366::aid-chem1366>3.0.co;2-k. Chemistry. 2000. PMID: 10840960
From Glycals to Glycopeptides: A Convergent and Stereoselective Total Synthesis of a High Mannose N-Linked Glycopeptide This work was supported by the National Institutes of Health (Grant Numbers AI16943/CA28824). We thank Dr. George Sukenick of the MSKCC NMR Core Facility for NMR and mass spectral analyses (NIH Grant Number: CA08748).
Wang ZG, Zhang X, Live D, Danishefsky SJ. Wang ZG, et al. Angew Chem Int Ed Engl. 2001 Feb 16;40(4):647. Angew Chem Int Ed Engl. 2001. PMID: 11241590 No abstract available.
From Glycals to Glycopeptides: A Convergent and Stereoselective Total Synthesis of a High Mannose N-Linked Glycopeptide This work was supported by the National Institutes of Health (Grant Numbers AI16943/CA28824). We thank Dr. George Sukenick of the MSKCC NMR Core Facility for NMR and mass spectral analyses (NIH Grant Number: CA08748).
Wang ZG, Zhang X, Live D, Danishefsky SJ. Wang ZG, et al. Angew Chem Int Ed Engl. 2000 Oct 16;39(20):3652-3656. doi: 10.1002/1521-3773(20001016)39:20<3652::aid-anie3652>3.0.co;2-b. Angew Chem Int Ed Engl. 2000. PMID: 11091428 No abstract available.
Toward Fully Synthetic Homogeneous Glycoproteins: A High Mannose Core Containing Glycopeptide Carrying Full H-Type 2 Human Blood Group Specificity This work was supported by the National Institutes of Health (Grant nos.: HL-25848 and CA-28824 (to S.J.D.), and CA-710506 (to K.O.L.)). Postdoctoral fellowship support is gratefully acknowledged by Z.-G.W. (US Army breast cancer grant no.: DAMD17-97-1-7119) and M.V. (NIH grant no.: CA-62948-04). We gratefully acknowledge Dr. George Sukenick of the Sloan-Kettering Institute's NMR core facility for mass spectral and NMR spectroscopic analyses (SKI core grant no.: CA-08748).
Wang ZG, Zhang X, Visser M, Live D, Zatorski A, Iserloh U, Lloyd KO, Danishefsky SJ. Wang ZG, et al. Angew Chem Int Ed Engl. 2001 May 4;40(9):1728-1732. Angew Chem Int Ed Engl. 2001. PMID: 11353493 No abstract available.
1,807 results