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A Conformational Change of Complement C5 Is Required for Thrombin-Mediated Cleavage, Revealed by a Novel Ex Vivo Human Whole Blood Model Preserving Full Thrombin Activity.
Nilsson PH, Johnson C, Quach QH, Macpherson A, Durrant O, Pischke SE, Fure H, Landsem A, Bergseth G, Schjalm C, Haugaard-Kedström LM, Huber-Lang M, van den Elsen J, Brekke OL, Mollnes TE. Nilsson PH, et al. J Immunol. 2021 Sep 15;207(6):1641-1651. doi: 10.4049/jimmunol.2001471. Epub 2021 Aug 11. J Immunol. 2021. PMID: 34380648 Free PMC article.
Mutational analyses reveal that the staphylococcal immune evasion molecule Sbi and complement receptor 2 (CR2) share overlapping contact residues on C3d: implications for the controversy regarding the CR2/C3d cocrystal structure.
Isenman DE, Leung E, Mackay JD, Bagby S, van den Elsen JM. Isenman DE, et al. Among authors: van den elsen jm. J Immunol. 2010 Feb 15;184(4):1946-55. doi: 10.4049/jimmunol.0902919. Epub 2010 Jan 18. J Immunol. 2010. PMID: 20083651
54 results