Nichols NF - Search Results

1

BACE knockout mice are healthy despite lacking the primary beta-secretase activity in brain: implications for Alzheimer's disease therapeutics.

Roberds SL, Anderson J, Basi G, Bienkowski MJ, Branstetter DG, Chen KS, Freedman SB, Frigon NL, Games D, Hu K, Johnson-Wood K, Kappenman KE, Kawabe TT, Kola I, Kuehn R, Lee M, Liu W, Motter R, Nichols NF, Power M, Robertson DW, Schenk D, Schoor M, Shopp GM, Shuck ME, Sinha S, Svensson KA, Tatsuno G, Tintrup H, Wijsman J, Wright S, McConlogue L. Roberds SL, et al. Among authors: nichols nf. Hum Mol Genet. 2001 Jun 1;10(12):1317-24. doi: 10.1093/hmg/10.12.1317. Hum Mol Genet. 2001. PMID: 11406613

2

PNU-96391A (OSU6162) antagonizes the development of behavioral sensitization induced by dopamine agonists in a rat model for Parkinson's disease.

Nichols NF, Cimini MG, Haas JV, Staton BA, Tedroff J, Svensson KA. Nichols NF, et al. Neuropharmacology. 2002 Oct;43(5):817-24. doi: 10.1016/s0028-3908(02)00144-2. Neuropharmacology. 2002. PMID: 12384167

3

Dopamine D(3) receptor antagonists. 1. Synthesis and structure-activity relationships of 5,6-dimethoxy-N-alkyl- and N-alkylaryl-substituted 2-aminoindans.

Haadsma-Svensson SR, Cleek KA, Dinh DM, Duncan JN, Haber CL, Huff RM, Lajiness ME, Nichols NF, Smith MW, Svensson KA, Zaya MJ, Carlsson A, Lin CH. Haadsma-Svensson SR, et al. Among authors: nichols nf. J Med Chem. 2001 Dec 20;44(26):4716-32. doi: 10.1021/jm010145w. J Med Chem. 2001. PMID: 11741489

4

2,3,4,5-tetrahydro- and 2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indoles: new templates for 5-HT(2C) agonists.

Ennis MD, Hoffman RL, Ghazal NB, Olson RM, Knauer CS, Chio CL, Hyslop DK, Campbell JE, Fitzgerald LW, Nichols NF, Svensson KA, McCall RB, Haber CL, Kagey ML, Dinh DM. Ennis MD, et al. Among authors: nichols nf. Bioorg Med Chem Lett. 2003 Jul 21;13(14):2369-72. doi: 10.1016/s0960-894x(03)00403-7. Bioorg Med Chem Lett. 2003. PMID: 12824036

5

Synthesis and biological activities of (R)-5,6-dihydro-N,N-dimethyl-4H-imidazo[4,5,1-ij]quinolin-5-amine and its metabolites.

Heier RF, Dolak LA, Duncan JN, Hyslop DK, Lipton MF, Martin IJ, Mauragis MA, Piercey MF, Nichols NF, Schreur PJ, Smith MW, Moon MW. Heier RF, et al. Among authors: nichols nf. J Med Chem. 1997 Feb 28;40(5):639-46. doi: 10.1021/jm960360q. J Med Chem. 1997. PMID: 9057850

6

Two automated locomotor activity tests for dopamine autoreceptor agonists.

Schreur PJ, Nichols NF. Schreur PJ, et al. Among authors: nichols nf. Pharmacol Biochem Behav. 1986 Jul;25(1):255-61. doi: 10.1016/0091-3057(86)90263-7. Pharmacol Biochem Behav. 1986. PMID: 2875471

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