MacNaul KL - Search Results

1

27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells.

Fu X, Menke JG, Chen Y, Zhou G, MacNaul KL, Wright SD, Sparrow CP, Lund EG. Fu X, et al. Among authors: macnaul kl. J Biol Chem. 2001 Oct 19;276(42):38378-87. doi: 10.1074/jbc.M105805200. Epub 2001 Aug 14. J Biol Chem. 2001. PMID: 11504730 Free article.

2

Design, synthesis, and structure-activity relationship of podocarpic acid amides as liver X receptor agonists for potential treatment of atherosclerosis.

Liu W, Chen S, Dropinski J, Colwell L, Robins M, Szymonifka M, Hayes N, Sharma N, MacNaul K, Hernandez M, Burton C, Sparrow CP, Menke JG, Singh SB. Liu W, et al. Bioorg Med Chem Lett. 2005 Oct 15;15(20):4574-8. doi: 10.1016/j.bmcl.2005.06.100. Bioorg Med Chem Lett. 2005. PMID: 16125384

3

A potent synthetic LXR agonist is more effective than cholesterol loading at inducing ABCA1 mRNA and stimulating cholesterol efflux.

Sparrow CP, Baffic J, Lam MH, Lund EG, Adams AD, Fu X, Hayes N, Jones AB, Macnaul KL, Ondeyka J, Singh S, Wang J, Zhou G, Moller DE, Wright SD, Menke JG. Sparrow CP, et al. Among authors: macnaul kl. J Biol Chem. 2002 Mar 22;277(12):10021-7. doi: 10.1074/jbc.M108225200. Epub 2002 Jan 14. J Biol Chem. 2002. PMID: 11790770 Free article.

4

A novel liver X receptor agonist establishes species differences in the regulation of cholesterol 7alpha-hydroxylase (CYP7a).

Menke JG, Macnaul KL, Hayes NS, Baffic J, Chao YS, Elbrecht A, Kelly LJ, Lam MH, Schmidt A, Sahoo S, Wang J, Wright SD, Xin P, Zhou G, Moller DE, Sparrow CP. Menke JG, et al. Among authors: macnaul kl. Endocrinology. 2002 Jul;143(7):2548-58. doi: 10.1210/endo.143.7.8907. Endocrinology. 2002. PMID: 12072387

5

Dual mechanisms of ABCA1 regulation by geranylgeranyl pyrophosphate.

Gan X, Kaplan R, Menke JG, MacNaul K, Chen Y, Sparrow CP, Zhou G, Wright SD, Cai TQ. Gan X, et al. J Biol Chem. 2001 Dec 28;276(52):48702-8. doi: 10.1074/jbc.M109402200. Epub 2001 Oct 18. J Biol Chem. 2001. PMID: 11641412 Free article.

6

Discovery and development of dimeric podocarpic acid leads as potent agonists of liver X receptor with HDL cholesterol raising activity in mice and hamsters.

Singh SB, Ondeyka JG, Liu W, Chen S, Chen TS, Li X, Bouffard A, Dropinski J, Jones AB, McCormick S, Hayes N, Wang J, Sharma N, Macnaul K, Hernandez M, Chao YS, Baffic J, Lam MH, Burton C, Sparrow CP, Menke JG. Singh SB, et al. Bioorg Med Chem Lett. 2005 Jun 2;15(11):2824-8. doi: 10.1016/j.bmcl.2005.03.100. Bioorg Med Chem Lett. 2005. PMID: 15911262

7

Anthrabenzoxocinones from Streptomyces sp. as liver X receptor ligands and antibacterial agents.

Herath KB, Jayasuriya H, Guan Z, Schulman M, Ruby C, Sharma N, MacNaul K, Menke JG, Kodali S, Galgoci A, Wang J, Singh SB. Herath KB, et al. J Nat Prod. 2005 Sep;68(9):1437-40. doi: 10.1021/np050176k. J Nat Prod. 2005. PMID: 16180833

8

Steroidal and triterpenoidal fungal metabolites as ligands of liver X receptors.

Ondeyka JG, Jayasuriya H, Herath KB, Guan Z, Schulman M, Collado J, Dombrowski AW, Kwon SS, McCallum C, Sharma N, MacNaul K, Hayes N, Menke JG, Singh SB. Ondeyka JG, et al. J Antibiot (Tokyo). 2005 Sep;58(9):559-65. doi: 10.1038/ja.2005.76. J Antibiot (Tokyo). 2005. PMID: 16320760

9

Guttiferone I, a new prenylated benzophenone from Garcinia humilis as a liver X receptor ligand.

Herath K, Jayasuriya H, Ondeyka JG, Guan Z, Borris RP, Stijfhoorn E, Stevenson D, Wang J, Sharma N, Macnaul K, Menke JG, Ali A, Schulman MJ, Singh SB. Herath K, et al. J Nat Prod. 2005 Apr;68(4):617-9. doi: 10.1021/np050045j. J Nat Prod. 2005. PMID: 15844964

10

Diterpenoid, steroid, and triterpenoid agonists of liver X receptors from diversified terrestrial plants and marine sources.

Jayasuriya H, Herath KB, Ondeyka JG, Guan Z, Borris RP, Tiwari S, de Jong W, Chavez F, Moss J, Stevenson DW, Beck HT, Slattery M, Zamora N, Schulman M, Ali A, Sharma N, MacNaul K, Hayes N, Menke JG, Singh SB. Jayasuriya H, et al. J Nat Prod. 2005 Aug;68(8):1247-52. doi: 10.1021/np050182g. J Nat Prod. 2005. PMID: 16124770

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