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Design, synthesis, and structure-activity relationship of podocarpic acid amides as liver X receptor agonists for potential treatment of atherosclerosis.
Liu W, Chen S, Dropinski J, Colwell L, Robins M, Szymonifka M, Hayes N, Sharma N, MacNaul K, Hernandez M, Burton C, Sparrow CP, Menke JG, Singh SB. Liu W, et al. Among authors: sparrow cp. Bioorg Med Chem Lett. 2005 Oct 15;15(20):4574-8. doi: 10.1016/j.bmcl.2005.06.100. Bioorg Med Chem Lett. 2005. PMID: 16125384
Different roles of liver X receptor alpha and beta in lipid metabolism: effects of an alpha-selective and a dual agonist in mice deficient in each subtype.
Lund EG, Peterson LB, Adams AD, Lam MH, Burton CA, Chin J, Guo Q, Huang S, Latham M, Lopez JC, Menke JG, Milot DP, Mitnaul LJ, Rex-Rabe SE, Rosa RL, Tian JY, Wright SD, Sparrow CP. Lund EG, et al. Among authors: sparrow cp. Biochem Pharmacol. 2006 Feb 14;71(4):453-63. doi: 10.1016/j.bcp.2005.11.004. Epub 2005 Dec 2. Biochem Pharmacol. 2006. PMID: 16325781
Dual mechanisms of ABCA1 regulation by geranylgeranyl pyrophosphate.
Gan X, Kaplan R, Menke JG, MacNaul K, Chen Y, Sparrow CP, Zhou G, Wright SD, Cai TQ. Gan X, et al. Among authors: sparrow cp. J Biol Chem. 2001 Dec 28;276(52):48702-8. doi: 10.1074/jbc.M109402200. Epub 2001 Oct 18. J Biol Chem. 2001. PMID: 11641412 Free article.
Discovery and development of dimeric podocarpic acid leads as potent agonists of liver X receptor with HDL cholesterol raising activity in mice and hamsters.
Singh SB, Ondeyka JG, Liu W, Chen S, Chen TS, Li X, Bouffard A, Dropinski J, Jones AB, McCormick S, Hayes N, Wang J, Sharma N, Macnaul K, Hernandez M, Chao YS, Baffic J, Lam MH, Burton C, Sparrow CP, Menke JG. Singh SB, et al. Among authors: sparrow cp. Bioorg Med Chem Lett. 2005 Jun 2;15(11):2824-8. doi: 10.1016/j.bmcl.2005.03.100. Bioorg Med Chem Lett. 2005. PMID: 15911262
Effects of pH and low density lipoprotein (LDL) on PCSK9-dependent LDL receptor regulation.
Fisher TS, Lo Surdo P, Pandit S, Mattu M, Santoro JC, Wisniewski D, Cummings RT, Calzetta A, Cubbon RM, Fischer PA, Tarachandani A, De Francesco R, Wright SD, Sparrow CP, Carfi A, Sitlani A. Fisher TS, et al. Among authors: sparrow cp. J Biol Chem. 2007 Jul 13;282(28):20502-12. doi: 10.1074/jbc.M701634200. Epub 2007 May 10. J Biol Chem. 2007. PMID: 17493938 Free article.
56 results