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Targeted pharmacological depletion of serum amyloid P component for treatment of human amyloidosis.
Pepys MB, Herbert J, Hutchinson WL, Tennent GA, Lachmann HJ, Gallimore JR, Lovat LB, Bartfai T, Alanine A, Hertel C, Hoffmann T, Jakob-Roetne R, Norcross RD, Kemp JA, Yamamura K, Suzuki M, Taylor GW, Murray S, Thompson D, Purvis A, Kolstoe S, Wood SP, Hawkins PN. Pepys MB, et al. Among authors: hutchinson wl. Nature. 2002 May 16;417(6886):254-9. doi: 10.1038/417254a. Nature. 2002. PMID: 12015594
Molecular dissection of Alzheimer's disease neuropathology by depletion of serum amyloid P component.
Kolstoe SE, Ridha BH, Bellotti V, Wang N, Robinson CV, Crutch SJ, Keir G, Kukkastenvehmas R, Gallimore JR, Hutchinson WL, Hawkins PN, Wood SP, Rossor MN, Pepys MB. Kolstoe SE, et al. Among authors: hutchinson wl. Proc Natl Acad Sci U S A. 2009 May 5;106(18):7619-23. doi: 10.1073/pnas.0902640106. Epub 2009 Apr 16. Proc Natl Acad Sci U S A. 2009. PMID: 19372378 Free PMC article.
Antibodies to human serum amyloid P component eliminate visceral amyloid deposits.
Bodin K, Ellmerich S, Kahan MC, Tennent GA, Loesch A, Gilbertson JA, Hutchinson WL, Mangione PP, Gallimore JR, Millar DJ, Minogue S, Dhillon AP, Taylor GW, Bradwell AR, Petrie A, Gillmore JD, Bellotti V, Botto M, Hawkins PN, Pepys MB. Bodin K, et al. Among authors: hutchinson wl. Nature. 2010 Nov 4;468(7320):93-7. doi: 10.1038/nature09494. Epub 2010 Oct 20. Nature. 2010. PMID: 20962779 Free PMC article.
Immunoradiometric assay for human serum amyloid P component.
Millar DJ, Hutchinson WL, Pepys MB. Millar DJ, et al. Among authors: hutchinson wl. J Immunol Methods. 2011 Aug 31;371(1-2):18-24. doi: 10.1016/j.jim.2011.06.010. Epub 2011 Jun 25. J Immunol Methods. 2011. PMID: 21708157
Isolation and characterization of pharmaceutical grade human pentraxins, serum amyloid P component and C-reactive protein, for clinical use.
Pepys MB, Gallimore JR, Lloyd J, Li Z, Graham D, Taylor GW, Ellmerich S, Mangione PP, Tennent GA, Hutchinson WL, Millar DJ, Bennett G, More J, Evans D, Mistry Y, Poole S, Hawkins PN. Pepys MB, et al. Among authors: hutchinson wl. J Immunol Methods. 2012 Oct 31;384(1-2):92-102. doi: 10.1016/j.jim.2012.07.013. Epub 2012 Jul 31. J Immunol Methods. 2012. PMID: 22867744 Free PMC article.
54 results