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Characterization of Salmonella enterica derivatives harboring defined aroC and Salmonella pathogenicity island 2 type III secretion system (ssaV) mutations by immunization of healthy volunteers.
Hindle Z, Chatfield SN, Phillimore J, Bentley M, Johnson J, Cosgrove CA, Ghaem-Maghami M, Sexton A, Khan M, Brennan FR, Everest P, Wu T, Pickard D, Holden DW, Dougan G, Griffin GE, House D, Santangelo JD, Khan SA, Shea JE, Feldman RG, Lewis DJ. Hindle Z, et al. Among authors: chatfield sn. Infect Immun. 2002 Jul;70(7):3457-67. doi: 10.1128/IAI.70.7.3457-3467.2002. Infect Immun. 2002. PMID: 12065485 Free PMC article.
Salmonella typhi and S typhimurium derivatives harbouring deletions in aromatic biosynthesis and Salmonella Pathogenicity Island-2 (SPI-2) genes as vaccines and vectors.
Khan SA, Stratford R, Wu T, Mckelvie N, Bellaby T, Hindle Z, Sinha KA, Eltze S, Mastroeni P, Pickard D, Dougan G, Chatfield SN, Brennan FR. Khan SA, et al. Among authors: chatfield sn. Vaccine. 2003 Jan 17;21(5-6):538-48. doi: 10.1016/s0264-410x(02)00410-3. Vaccine. 2003. PMID: 12531654
Optimization of Salmonella enterica serovar typhi DeltaaroC DeltassaV derivatives as vehicles for delivering heterologous antigens by chromosomal integration and in vivo inducible promoters.
Stratford R, McKelvie ND, Hughes NJ, Aldred E, Wiseman C, Curtis J, Bellaby T, Bentley M, Hindle Z, Brennan FR, Chatfield SN, Dougan G, Khan SA. Stratford R, et al. Among authors: chatfield sn. Infect Immun. 2005 Jan;73(1):362-8. doi: 10.1128/IAI.73.1.362-368.2005. Infect Immun. 2005. PMID: 15618173 Free PMC article.
Ability of SPI2 mutant of S. typhi to effectively induce antibody responses to the mucosal antigen enterotoxigenic E. coli heat labile toxin B subunit after oral delivery to humans.
Khan S, Chatfield S, Stratford R, Bedwell J, Bentley M, Sulsh S, Giemza R, Smith S, Bongard E, Cosgrove CA, Johnson J, Dougan G, Griffin GE, Makin J, Lewis DJ. Khan S, et al. Vaccine. 2007 May 22;25(21):4175-82. doi: 10.1016/j.vaccine.2007.03.007. Epub 2007 Mar 21. Vaccine. 2007. PMID: 17412462 Free PMC article. Clinical Trial.
79 results