Margot NA - Search Results

1

Molecular mechanisms of resistance to human immunodeficiency virus type 1 with reverse transcriptase mutations K65R and K65R+M184V and their effects on enzyme function and viral replication capacity.

White KL, Margot NA, Wrin T, Petropoulos CJ, Miller MD, Naeger LK. White KL, et al. Among authors: margot na. Antimicrob Agents Chemother. 2002 Nov;46(11):3437-46. doi: 10.1128/AAC.46.11.3437-3446.2002. Antimicrob Agents Chemother. 2002. PMID: 12384348 Free PMC article.

2

Human immunodeficiency virus type 1 reverse transcriptase expressing the K70E mutation exhibits a decrease in specific activity and processivity.

Miller MD, Lamy PD, Fuller MD, Mulato AS, Margot NA, Cihlar T, Cherrington JM. Miller MD, et al. Among authors: margot na. Mol Pharmacol. 1998 Aug;54(2):291-7. doi: 10.1124/mol.54.2.291. Mol Pharmacol. 1998. PMID: 9687570

3

Prophylactic and therapeutic benefits of short-term 9-[2-(R)-(phosphonomethoxy)propyl]adenine (PMPA) administration to newborn macaques following oral inoculation with simian immunodeficiency virus with reduced susceptibility to PMPA.

Van Rompay KK, Miller MD, Marthas ML, Margot NA, Dailey PJ, Canfield DR, Tarara RP, Cherrington JM, Aguirre NL, Bischofberger N, Pedersen NC. Van Rompay KK, et al. Among authors: margot na. J Virol. 2000 Feb;74(4):1767-74. doi: 10.1128/jvi.74.4.1767-1774.2000. J Virol. 2000. PMID: 10644348 Free PMC article.

4

In vitro selection and characterization of HIV-1 with reduced susceptibility to PMPA.

Wainberg MA, Miller MD, Quan Y, Salomon H, Mulato AS, Lamy PD, Margot NA, Anton KE, Cherrington JM. Wainberg MA, et al. Among authors: margot na. Antivir Ther. 1999;4(2):87-94. doi: 10.1177/135965359900400205. Antivir Ther. 1999. PMID: 10682153

5

Increased drug susceptibility of HIV-1 reverse transcriptase mutants containing M184V and zidovudine-associated mutations: analysis of enzyme processivity, chain-terminator removal and viral replication.

Naeger LK, Margot NA, Miller MD. Naeger LK, et al. Among authors: margot na. Antivir Ther. 2001 Jun;6(2):115-26. Antivir Ther. 2001. PMID: 11491416

6

Adefovir and tenofovir susceptibilities of HIV-1 after 24 to 48 weeks of adefovir dipivoxil therapy: genotypic and phenotypic analyses of study GS-96-408.

Miller MD, Margot NA, Lamy PD, Fuller MD, Anton KE, Mulato AS, Cherrington JM. Miller MD, et al. Among authors: margot na. J Acquir Immune Defic Syndr. 2001 Aug 15;27(5):450-8. doi: 10.1097/00126334-200108150-00005. J Acquir Immune Defic Syndr. 2001. PMID: 11511821 Clinical Trial.

7

Tenofovir, adefovir, and zidovudine susceptibilities of primary human immunodeficiency virus type 1 isolates with non-B subtypes or nucleoside resistance.

Palmer S, Margot N, Gilbert H, Shaw N, Buckheit R Jr, Miller M. Palmer S, et al. AIDS Res Hum Retroviruses. 2001 Aug 10;17(12):1167-73. doi: 10.1089/088922201316912772. AIDS Res Hum Retroviruses. 2001. PMID: 11522186

8

Antiviral activity of tenofovir (PMPA) against nucleoside-resistant clinical HIV samples.

Miller MD, Margot NA, Hertogs K, Larder B, Miller V. Miller MD, et al. Among authors: margot na. Nucleosides Nucleotides Nucleic Acids. 2001 Apr-Jul;20(4-7):1025-8. doi: 10.1081/NCN-100002483. Nucleosides Nucleotides Nucleic Acids. 2001. PMID: 11562951

9

Tenofovir (PMPA) is less susceptible to pyrophosphorolysis and nucleotide-dependent chain-terminator removal than zidovudine or stavudine.

Naeger LK, Margot NA, Miller MD. Naeger LK, et al. Among authors: margot na. Nucleosides Nucleotides Nucleic Acids. 2001 Apr-Jul;20(4-7):635-9. doi: 10.1081/NCN-100002340. Nucleosides Nucleotides Nucleic Acids. 2001. PMID: 11563081

10

Genotypic and phenotypic analyses of HIV-1 in antiretroviral-experienced patients treated with tenofovir DF.

Margot NA, Isaacson E, McGowan I, Cheng AK, Schooley RT, Miller MD. Margot NA, et al. AIDS. 2002 Jun 14;16(9):1227-35. doi: 10.1097/00002030-200206140-00004. AIDS. 2002. PMID: 12045487 Clinical Trial.

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