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PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program.
Hashimoto M, Araki K, Cardenas MA, Li P, Jadhav RR, Kissick HT, Hudson WH, McGuire DJ, Obeng RC, Wieland A, Lee J, McManus DT, Ross JL, Im SJ, Lee J, Lin JX, Hu B, West EE, Scharer CD, Freeman GJ, Sharpe AH, Ramalingam SS, Pellerin A, Teichgräber V, Greenleaf WJ, Klein C, Goronzy JJ, Umaña P, Leonard WJ, Smith KA, Ahmed R. Hashimoto M, et al. Among authors: smith ka. Nature. 2022 Oct;610(7930):173-181. doi: 10.1038/s41586-022-05257-0. Epub 2022 Sep 28. Nature. 2022. PMID: 36171288 Free PMC article.
PD-L1 blockade synergizes with IL-2 therapy in reinvigorating exhausted T cells.
West EE, Jin HT, Rasheed AU, Penaloza-Macmaster P, Ha SJ, Tan WG, Youngblood B, Freeman GJ, Smith KA, Ahmed R. West EE, et al. Among authors: smith ka. J Clin Invest. 2013 Jun;123(6):2604-15. doi: 10.1172/JCI67008. Epub 2013 May 15. J Clin Invest. 2013. PMID: 23676462 Free PMC article.
1,155 results