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Design and synthesis of aminophenol-based factor Xa inhibitors.
Wu S, Guilford WJ, Chou YL, Griedel BD, Liang A, Sakata S, Shaw KJ, Trinh L, Xu W, Zhao Z, Morrissey MM. Wu S, et al. Among authors: chou yl. Bioorg Med Chem Lett. 2002 May 6;12(9):1307-10. doi: 10.1016/s0960-894x(02)00142-7. Bioorg Med Chem Lett. 2002. PMID: 11965377
Indolinone based phosphoinositide-dependent kinase-1 (PDK1) inhibitors. Part 1: design, synthesis and biological activity.
Islam I, Bryant J, Chou YL, Kochanny MJ, Lee W, Phillips GB, Yu H, Adler M, Whitlow M, Ho E, Lentz D, Polokoff MA, Subramanyam B, Wu JM, Zhu D, Feldman RI, Arnaiz DO. Islam I, et al. Among authors: chou yl. Bioorg Med Chem Lett. 2007 Jul 15;17(14):3814-8. doi: 10.1016/j.bmcl.2007.04.071. Epub 2007 Apr 27. Bioorg Med Chem Lett. 2007. PMID: 17531483
Thiophene-anthranilamides as highly potent and orally available factor Xa inhibitors.
Ye B, Arnaiz DO, Chou YL, Griedel BD, Karanjawala R, Lee W, Morrissey MM, Sacchi KL, Sakata ST, Shaw KJ, Wu SC, Zhao Z, Adler M, Cheeseman S, Dole WP, Ewing J, Fitch R, Lentz D, Liang A, Light D, Morser J, Post J, Rumennik G, Subramanyam B, Sullivan ME, Vergona R, Walters J, Wang YX, White KA, Whitlow M, Kochanny MJ. Ye B, et al. Among authors: chou yl. J Med Chem. 2007 Jun 28;50(13):2967-80. doi: 10.1021/jm070125f. Epub 2007 May 31. J Med Chem. 2007. PMID: 17536795
The discovery of fluoropyridine-based inhibitors of the Factor VIIa/TF complex.
Kohrt JT, Filipski KJ, Cody WL, Cai C, Dudley DA, Van Huis CA, Willardsen JA, Rapundalo ST, Saiya-Cork K, Leadley RJ, Narasimhan L, Zhang E, Whitlow M, Adler M, McLean K, Chou YL, McKnight C, Arnaiz DO, Shaw KJ, Light DR, Edmunds JJ. Kohrt JT, et al. Among authors: chou yl. Bioorg Med Chem Lett. 2005 Nov 1;15(21):4752-6. doi: 10.1016/j.bmcl.2005.07.059. Bioorg Med Chem Lett. 2005. PMID: 16125385
177 results