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Design and synthesis of statine-based cell-permeable peptidomimetic inhibitors of human beta-secretase.
J Med Chem. 2003 May 8;46(10):1799-802. doi: 10.1021/jm025619l.
J Med Chem. 2003.
PMID: 12723942
Design and synthesis of hydroxyethylamine (HEA) BACE-1 inhibitors: structure-activity relationship of the aryl region.
Probst GD, Bowers S, Sealy JM, Stupi B, Dressen D, Jagodzinska BM, Aquino J, Gailunas A, Truong AP, Tso L, Xu YZ, Hom RK, John V, Tung JS, Pleiss MA, Tucker JA, Konradi AW, Sham HL, Jagodzinski J, Toth G, Brecht E, Yao N, Pan H, Lin M, Artis DR, Ruslim L, Bova MP, Sinha S, Yednock TA, Gauby S, Zmolek W, Quinn KP, Sauer JM.
Probst GD, et al.
Bioorg Med Chem Lett. 2010 Oct 15;20(20):6034-9. doi: 10.1016/j.bmcl.2010.08.070. Epub 2010 Aug 19.
Bioorg Med Chem Lett. 2010.
PMID: 20822903
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Design and synthesis of hydroxyethylamine (HEA) BACE-1 inhibitors: prime side chromane-containing inhibitors.
Ng RA, Sun M, Bowers S, Hom RK, Probst GD, John V, Fang LY, Maillard M, Gailunas A, Brogley L, Neitz RJ, Tung JS, Pleiss MA, Konradi AW, Sham HL, Dappen MS, Adler M, Yao N, Zmolek W, Nakamura D, Quinn KP, Sauer JM, Bova MP, Ruslim L, Artis DR, Yednock TA.
Ng RA, et al.
Bioorg Med Chem Lett. 2013 Aug 15;23(16):4674-9. doi: 10.1016/j.bmcl.2013.06.006. Epub 2013 Jun 11.
Bioorg Med Chem Lett. 2013.
PMID: 23856050
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Design and synthesis of hydroxyethylene-based peptidomimetic inhibitors of human beta-secretase.
Hom RK, Gailunas AF, Mamo S, Fang LY, Tung JS, Walker DE, Davis D, Thorsett ED, Jewett NE, Moon JB, John V.
Hom RK, et al. Among authors: gailunas af.
J Med Chem. 2004 Jan 1;47(1):158-64. doi: 10.1021/jm0304008.
J Med Chem. 2004.
PMID: 14695829
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